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Paper Detail

Paper IDMLR-APPL-BSIP.6
Paper Title EFFORT-FREE AUTOMATED SKELETAL ABNORMALITY DETECTION OF RAT FETUSES ON WHOLE-BODY MICRO-CT SCANS
Authors Akihiro Fukuda, Changhee Han, Kazumi Hakamada, LPIXEL Inc., Japan
SessionMLR-APPL-BSIP: Machine learning for biomedical signal and image processing
LocationArea C
Session Time:Wednesday, 22 September, 08:00 - 09:30
Presentation Time:Wednesday, 22 September, 08:00 - 09:30
Presentation Poster
Topic Applications of Machine Learning: Machine learning for biomedical signal and image processing
IEEE Xplore Open Preview  Click here to view in IEEE Xplore
Abstract Machine Learning-based fast and quantitative automated screening plays a key role in analyzing human bones on Computed Tomography (CT) scans. However, despite the requirement in drug safety assessment, such research is rare on animal fetus micro-CT scans due to its laborious data collection and annotation. Therefore, we propose various bone feature engineering techniques to thoroughly automate the skeletal localization/labeling/abnormality detection of rat fetuses on whole-body micro-CT scans with minimum effort. Despite limited training data of 49 fetuses, in skeletal labeling and abnormality detection, we achieve accuracy of 0.900 and 0.810, respectively.